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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic plants other than algae

Administrative data

Endpoint:
toxicity to aquatic plants other than algae
Remarks:
Microbial reduction of the substance by algae
Type of information:
experimental study
Adequacy of study:
other information
Study period:
1992
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Microbial Reduction of Cyclohexanone by Chlorella pyrenoidosa Chick
Author:
Yoshizako, F., Nishimura, A., Mitsuo, C.
Year:
1992
Bibliographic source:
J. of Fermentation and Bioengineering Vol. 74, No. 6, 395-397. 1992

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Reduction of the test substance by algae was determined by GC analysis of the transformation product cyclooctanol.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Cyclooctanone
EC Number:
207-940-2
EC Name:
Cyclooctanone
Cas Number:
502-49-8
Molecular formula:
C8H14O
IUPAC Name:
cyclooctanone

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
Metabolites were extracted from culture medium with trimethylsilyl ether (TMS).

Test organisms

Test organisms (species):
other: Chlorella pyrenoidosa Chick
Details on test organisms:
strain NIES-226

Study design

Test type:
static
Water media type:
not specified
Total exposure duration:
72 h

Test conditions

Test temperature:
25 °C
pH:
6.5
Nominal and measured concentrations:
0.2% test substance in the test medium

Results and discussion

Details on results:
After incubation of the test substance with the algae, the transformation metabolite Cyclooctanol could be detected by GC analysis.

Applicant's summary and conclusion

Conclusions:
The data demonstrates reductive conversion of alicyclic ketones to alcohols in Chlorella. The algae C. pyrenoidosa is able to reduce cyclooctanone. Cyclooctanol is suggested as transformation product.