Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 224-736-9 | CAS number: 4468-02-4
Endpoint summary
Administrative data
Description of key information
The following endpoints are reported:
- Short-term toxicity to fish:
An OECD 203 study (GLP) was conducted on Oncorhynchus mykiss under semi-static conditions. This study is considered reliable. The EC-96h determined on Oncorhynchus mykiss is 11.12mg/L (confidence limits (95%): 10-10mg/L).
- Short-term toxicity to aquatic invertebrates:
The study is an acute toxicity test performed on Daphnia Magna according to the OECD 202 guidline and to GLP. This study is considered reliable and it is used for assessment. The EC50-48h was determined on Daphnia Magna at 22.8mg/L (Confidence limits (95%) 20.4-25.3 mg/L).
- Toxicity to aquatic algae and cyanobacteria:
An EC50 -72h on pseudokirchneriella subcapitata is determined at 0.26mg/L. This resulte is reliable an used for assessment.
Several EC50 and EC10 are provided as a weight of evidence, by different studies identified in a read-across approach. All these values established in these studies are in the same order of magnitude. They support the result of the experimental study.
- Toxicity to microorganisms:
As reported in the Eu risk assessment report (EU RAR 2010), the activated sludge respiration inhibition test reported by Dutka et al. (1983) showed the lowest useful EC50 value (for bacteria) for Zinc compounds, with a 3-h EC50 of 5,200μg/l. This value is considered for assessment in a read-across approach.
Additional information
Considering that:
- 96 hr LC50 (for fish) > 1 mg/l
- 48 hr EC50 (for crustacea) > 1 mg/l
- 72 or 96 hr ErC50 (for algae or other aquatic plants) < 1 mg/l (determined at 0.26mg/l)
the substance is classified as Category 1 regarding acute aquatic toxicity to the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
