Bis(D-gluconato-O1,O2)zinc

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 23 to 23 March 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

GLP compliance:

not specified

Type of method:

capillary method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 1700001575
- Expiration date of the lot/batch :09.08.2020
- Manufacturing date: 10.08.2017

Key result

Melting / freezing pt.:

89.5 °C

Atm. press.:

996.1 hPa

Decomposition:

yes

Remarks on result:

other: Average values ± standard deviations ± 2.2°C

Melting / freezing pt.:

92 °C

Atm. press.:

996.1 hPa

Decomposition:

yes

Remarks on result:

other: tint changes from white to grey at 92°C

Melting / freezing pt.:

88.2 °C

Atm. press.:

996.1 hPa

Decomposition:

yes

Remarks on result:

other: tint changes from white to grey at 88.2 °C. shape changes (narrowing) at 88.2 °C.

The preliminary study and measurements were performed under atmospheric pressure of 996.1 hPa. The study was carried out in order to determine the melting temperature range forZinc Gluconate (50.0 – 400.0°C).

Preliminary test

At 87.5°C when heated at 10.0 ˚Cper minute narrowing of the substance column and change in color from white to grey was observed (the beginning of decomposition).

Final test

The three series of melting point measurements were performed in the temperature range 78.0 - 400.0 °C. The heating rate was 0.5°C/min.

Samples number 2 and 3 started to change the shape (narrowing) and tint from white to grey at 88.2 °C. Sample number 1 started to change the tint (white to grey) at 92.0 °C.

The average value of initial decomposition temperature for the three samples of Zinc Gluconate is 89.5 ± 2.2 °C.

Accuracy :

The measuring accuracy depends on the BÜCHI Melting Point M-565 apparatus accuracy (the accuracy of the apparatus is defined as: up to 250.0°C is equal to 0.3 °C, 250.0 - 400.0 °C is equal to 0.3°C - 0.5°C). In this study, the accuracy of the apparatus was equal to 0.3°C.

Conclusions:

The determination of melting point of test item is carried out in accordance with the OECD 102 guideline.
The average melting temperature of the test item is determinated to be 89.5 ± 2.2 °C at atmospheric pressure.

Description of key information

The determination of melting point of test item is carried out in accordance with the OECD 102 guideline.

The average melting temperature of the test item is determinated to be 89.5 ± 2.2 °C at atmospheric pressure.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

89.5 °C