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EC number: 500-092-7
CAS number: 36890-68-3
Persistence: Based on a reliable study to determine the ready
biodegradability for the test substance, it was concluded that
e-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol is
readily biodegradable with >90% degradation in 28 days. The substance
is not P or vP.
Bioaccumulation: The weighted average Log Pow value of e-Caprolactone,
oligomeric reaction products with 2,2’-oxydiethanol is 1.8 indicating
the potential for bioaccumulation is low. In addition, the test
substance is readily and rapidly biodegradable indicating the
potential to remain in water and accumulate through aquatic food
chains is low.The substance is not B or vB.
Toxicity: There are three reliable (Klimisch 1 and 2) studies
available for three trophic levels; fish, aquatic invertebrates and
algae. The lowest short-term toxicity EC/LC50 was determined to be
33.14 and 6.29 mg/l to aquatic algae, based on geometric mean measured
concentrations of the two measured components of the test substance
and these do not meet the T criterion.
One long-term endpoint is available from the algal study, but the EC10
values are not biologically relevant for adverse effects on algal
growth with a mean inhibition of growth at 4.7% due to the low
substance stability in the test medium. The substance is rapidly
biodegradable (meets the 10-day window) and not considered to pose a
long-term hazard to aquatic organisms. The acute toxicity data for the
three trophic levels of organism are relied upon for the PBT
assessment of the test substance. Also, based on the available
toxicological information available, the substance does not meet the
criteria for classification as carcinogenic (category 1A or 1B), germ
cell mutagenic (category 1A or 1B), or toxic for reproduction
(category 1A, 1B or 2) according to Regulation EC No 1272/2008. The
substance does not meet the criteria for classification as specific
target organ toxicity after repeated exposure (STOT RE category 1 or
2) according to Regulation EC No 1272/2008. Therefore, the substance
is not T.
The overall conclusion is that the test substance, e-Caprolactone,
oligomeric reaction products with 2,2’-oxydiethanol is not PBT or
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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