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EC number: 624-182-1
CAS number: 4187-38-6
The test substance rac-1-(3-Methoxyphenyl)ethylamine (read across, CAS
62409-13-6) is not mutagenic in the Salmonella typhimurium/Escherichia
coli reverse mutation assay (OECD 471).
According to the results of the present
study, the test substance rac-1-(3-Methoxyphenyl)ethylamine (read
across, CAS 62409-13-6) did not lead to an increase in the number of
revertant colonies either without S9 mix or after adding a metabolizing
system in two experiments carried out independently of each other
(standard plate test and preincubation assay). Besides, the results of
the negative as well as the positive controls performed in parallel
corroborated the validity of this study, since the values fulfilled the
acceptance criteria of this study. In this study with and without S9
mix, the number of revertant colonies in the negative controls was
within the range of the historical negative control data for each tester
strain. In addition, the positive control substances both with and
without S9 mix induced a significant increase in the number of revertant
colonies within the range of the historical positive control data or
above. [BASF, 2013]
Based on the available data for
rac-1-(3-Methoxyphenyl)ethylamine (read across, CAS 62409-13-6) (R)-1
-(4 -Methylphenyl)ethylamine is not subject to C&L (according to
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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