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EC number: 271-089-3
CAS number: 68515-47-9
The High Molecular Weight Phthalate Ester (HMWPE) Category consists of
phthalate esters with an alkyl carbon backbone with 7 carbon (C7) atoms
or greater. The category is formed on the principle that substances of
similar structure have similar toxicological properties. The data
available on high molecular weight phthalates demonstrate that members
of this category have similar biological activities and toxicological
properties; verifying the use of read-across data as an appropriate
approach to characterize endpoints. DTDP (C13) is a
high molecular weight phthalate ester. Where data
maybe lacking for DTDP, DINP (C9) and DIDP (C10), which are also high
molecular weight phthalate esters, are used as read-across substances to
provide toxicological information.
Like other high molecular weight phthalates, DTDP was not mutagenic in
vitro in bacterial mutation assays (with and without metabolic
activation). The structurally similar compound DIDP is not clastogenic
in the mouse micronucleus assay in vivo. Based on
these data, DTDP is not mutagenic or genotoxic.
No classification for genetic toxicity or mutagenicity is indicated
according to the general classification and labeling requirements for
dangerous substances and preparations (Directive 67-548-EEC) or the
classification, labeling and packaging (CLP) regulation (EC) No
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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