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EC number: 271-089-3
CAS number: 68515-47-9
The key parameter is a calculated value. However, additional measured data for analogs from a biomagnification study support the use of the of the calculated value to characterize the BCF of DTDP, and suggest that DTDP has a low bioaccumulative potential, not expected to accumulate through food chains in the aquatic environment.
of a study to assess the bioaccumulative potential of high molecular
weight phthalate diesters, di-C8
PEs to di-C10 PEs, in an aquatic
food-web that included 18 marine species, showed that high molecular
weight phthalate esters did not biomagnify, but rather decreased in
tissue concentration in organisms of increasing trophic position.
Decreasing concentrations also referred to as biodilution, can be
quantified by food-web magnification factors (FWMFs). A FWMF that is
greater than 1.0 is an indication of chemical biomagnification within a
food-web, whereas a value of less than 1.0 indicates biodilution ordecreasing
concentrationsfrom lower to
higher trophic levels. Study results showed that lipid equivalent
concentrations of the high molecular weight phthalate diesters
significantly declined with increasing trophic level and that the FWMFfor
di-isodecyl phthalate was 0.44. Similar results would be expected with
DTDP, an analog of DIDP(Mackintoshet
finding above is consistent with a laboratory fish bioaccumulation study
in which rainbow trout were fed a DTDP spiked diet for 9 days(ExxonMobil,
low water solubility and high Kowof DTDP prevent conducting
an aqueous exposure BCF (bioconcentration factor) study. At
the end of the exposure period, fish were sampled after different
depuration times (0, 1, 3 days). Results demonstrated a low potential
for bioaccumulation with a lipid normalized biomagnification factor
(BMF, concentration ratio in tissue to that in diet) of <0.1 and rapid
subsequent depuration with a tissue elimination half-life of <1 day. The
half-life of <1 day was used to calculate a BCF in fish of approximately
<1 L/kg for DINP.
bioconcentration factor (BCF) value, 3.2 (log BCF = 0.5), is estimated
for DTDP using theU.S. Environmental Protection Agency
model, EPI SuiteTM(USEPA,
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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