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EC number: 271-089-3
CAS number: 68515-47-9
In this study, 20 guinea pigs were exposed to DTDP in a skin
sensitization exposure paradigm utilizing and induction and challenge
phase in the method of the Buehler test. A 20 x 20 mm patch of surgical
gauze was saturated with approximately 0.5 ml of test material was
placed on the skin and covered by an impermeable plastic adhesive tape.
Contact with the skin was maintained for approximately 6 hours. The
dressings were then removed and the resulting dermal reactions assessed
approximately 24 hours later. Inductions were conducted on days 1, 8,
and 15. The challenge application was given topically two weeks after
the induction via the same method and scored for dermal reactions 24, 48
and 72 hours post exposure. In all cases, DTDP did not produce any
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