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EC number: 222-048-3
CAS number: 3327-22-8
Acute and chronic aquatic toxicity
test results are used in the risk assessment. Aquatic toxicity against
aquatic invertebrates, fish and algae is addressed by experimental
results. Chronic values are available for Daphnia and algae. As Daphnia
magna was the most sensitive organism in acute toxicity tests a
long-term study according to OECD 211 and GLP was conducted (Noack
2004). Within this study the lowest effect concentration was determined
with a 21-d NOEC of 0.51 mg/L.
In acute aquatic toxicity tests the
effect concentrations were above 1 mg/L (lowest acute EC50 is a 48-h
EC50 (D. magna) of 164 mg/L). No acute classification is needed.
In a weight of evidence approach
(3-chloro-2-hydroxypropyl)trimethylammonium chloride (CHPTAC) was rated
as not readily biodegradable. In chronic aquatic toxicity tests, the
test item revealed NOEC values ≤ 1 mg/L and ≥ 0.1 mg/L, and thus needs
to be classified as hazardous to the aquatic environment in accordance
with Section 220.127.116.11., Annex I of Regulation 1272/2008/EC. As the test
item is not considered readily biodegradable, the relevant
classification is Aquatic Chronic 2 (H411).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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