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EC number: 222-048-3
CAS number: 3327-22-8
From the two available guideline
studies (modified Sturm test (OECD 301B) and STP simulation test (OECD
303A)) it can be concluded that CHPTAC is not readily biodegradable.
In other, non-standard tests some
removal of CHPTAC has been observed. The conclusion of the ESR Risk
Assessment for CHPTAC was that the substance could be considered
"inherently biodegradable not meeting specific criteria (cited from
European Union Risk Assessment Report on CAS # 3327-22-8, 2008).
Nevertheless, the test substance is
considered to be vP (and P).
CHPTAC has a partition coefficient
(log Kow) < -1.5 hence lacks any bioaccumulation potential.
Daphnia magna was identified as most
sensitive organism in the tests for aquatic toxicity with a 21-d NOEC of
0.51 mg/L (nominal).
Based on these data, the substance
does fulfil the REACH Annex XIII criteria for non-T properties
(EC10/NOEC ≥ 0.01 mg/L for marine/freshwater organisms (long-term
Furthermore, the substance is neither
classified as carcinogenic (category 1A or 1B), mutagenic (category 1A
or 1B), or toxic for reproduction (category 1A or 1B, or 2), nor is
there other evidence of chronic toxicity, as identified by the
classifications "STOT RE 1, or STOT RE 2" according to EU CLP Regulation.
In conclusion, CHPTAC is not readily
biodegradable, not bioaccumulating, and does not fulfil any of the
T-criteria. Therefore, the substance does not qualify for classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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