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EC number: 292-697-5
CAS number: 90989-41-6
cross-over analysis of logarithmic Pupillary Unrest Index (PUI) values
did not show an effect of toluene exposure. In a nonparametric
cross-over analysis of SPES-scores a significant increase of the scores
of unpleasant smell and irritation to the throat, but not of tiredness
was found. In conclusion, acute exposure to 50 ppm toluene did not
healthy men were exposed to a constant level of 50 ppm toluene. The
Pupillographic Sleepiness Test (PST) was performed before and after 4.5
h of exposure. Acute symptoms were assessed with the Swedish Performance
Evaluation System (SPES) self-assessment questionnaire, once before and
3 times during exposure. There was no effect of toluene exposure on PST
or tiredness but scores for unpleasant smell and irritation to the
throat were increased.
conclusion, a NOAEC of 50 ppm (192mg/m3) can be determined for acute
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