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EC number: 265-058-3
CAS number: 64741-57-7
A complex combination of hydrocarbons produced by the vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and boiling in the range of approximately 350°C to 600°C (662°F to 1112°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.
In both cases, significant and reproducible
dose-dependent increases in the number of revertants were obtained.
mutagenic potential of catalytic cracked clarified oil (up to 50000
µg/plate; sample API 81-15) was investigated in a non-guideline
GLP-compliant study. Four separate tests were conducted in duplicate
using S. typhimurium strain TA 98 in the presence of either 10%
Aroclor 1254-induced rat liver S9 mix and 4 mM NADP or 80% S9 mix and 12
mM NADP; 2-aminoanthracene and perylene were used as positive control
substances. A two-fold increase in revertants per plate was regarded as
a positive response.
test substance was positive in all 4 tests, with the number of
revertants increased maximally 13.1, 27.8, 44 and 46.3-fold,
respectively over solvent controls. The largest increase in revertants
occurred in the assays activated with 80% S-9 and 12 mM NADP. A
satisfactory response was obtained with the positive control substances.
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