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EC number: 265-058-3
CAS number: 64741-57-7
A complex combination of hydrocarbons produced by the vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and boiling in the range of approximately 350°C to 600°C (662°F to 1112°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.
No deaths resulted and there were no
significant clinical signs. Any erythema that may have
been present after patch removal was obscured by the black tarry test
The test substance was administered to
clipped skin from groups of male and female NW rabbits (n = 4/sex) at
2000 mg/kg bw followed by a 14 day observation period.
The test site from 2 animals per sex was
lightly abraded prior to dosing. There were no clinical signs or
evidence of systemic toxicity, and all animals gained weight during the
post-treatment period. No lesions were present at scheduled necropsy.
The acute dermal LD50 was >2000
mg/kg bw in both sexes.
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