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EC number: 265-058-3
CAS number: 64741-57-7
A complex combination of hydrocarbons produced by the vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and boiling in the range of approximately 350°C to 600°C (662°F to 1112°F). This stream is likely to contain 5 wt. % or more of 4- to 6-membered condensed ring aromatic hydrocarbons.
In addition to mortalities, the main
clinical signs were hypoactivity, ataxia, prostration, diarrhoea, hair
loss and eye opacity. The LD50 values for
male and female animals were 5270 and 4320 mg/kg respectively.
The test substance was administered to
groups of fasted male and female SD rats (n = 5/sex) at dose levels of
3200 – 7810 mg/kg bw followed by a 14 day observation period.
Variable mortality was present at treatment
levels of 4000 mg/kg bw and above, with complete mortality in the high
dose group. The main clinical signs were hypoactivity, ataxia,
prostration, diarrhoea, hair loss and eye opacity but no lesions were
visible at scheduled necropsy in survivors.
The acute oral LD50 was 4320
mg/kg bw in females and 5270 mg/kg bw in males.
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