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EC number: 229-222-8
CAS number: 6440-58-0
Annex IX of Regulation (EC) No 1907/2006, it is laid down that
short-term toxicity to terrestrial organisms shall be proposed by the
registrant if the chemical safety assessment indicates the need to
investigate further the effects of the substance and/or relevant
degradation products on terrestrial organisms. Column
2 of Annex IX states that studies do not need to be conducted if direct
and indirect exposure of the soil compartment is unlikely.
information, there are no reliable toxicity data for soil-dwelling
organisms relating to DMDMH. However,
reliable toxicity data for terrestrial organisms is available for DMH,
the hydrolysis product of DMDMH. DMDMH
readily undergoes hydrolysis to DMH and therefore data are provided for
both substances when available. In the case of long-term testing, the
data on DMH are considered more relevant for environmental fate and
ecotoxicology and are provided in this dossier for information.
can be concluded that short-term toxicity testing of terrestrial
organisms is not required based on the unlikely direct or indirect
exposure of soil organisms to the DMDMH product or its degradation
product (DMH). Based on the unlikely direct exposure to soil organisms,
rapid biodegradability in the environment and the additional evidence of
no toxicity observed in soil microbes, plants or soil macroinvertebrates
in long- and short-term toxicity testing of the breakdown product.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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