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EC number: 206-996-5
CAS number: 420-46-2
1,1,1 -trifluoroethane is a gas with a boiling point of -47.4 deg C. It
is therefore difficult to dissolve in water and will rapidly partition
into the air. For that reason, aquatic toxicity studies were limited. It
had a 96 -hr LC50 in trout of > 40mg/l (analytically measured), nominal
350 mg/l. EcoSar model v0.99 predicted 109 mg/l for fish. The 48 -hr
EC50 for daphnia was determined to be 300 mg/l (analytically
determined). EcoSar model v0.99 predicted the EC50 to be 115 mg/l for
Daphnia. At the time 1,1,1-trifluoroethane was being studied, test
methods did not exist to study the effects of such volatile materials on
algae. Data on 1 -chloro-1,1 -difluoroethane was used as a read across
substance. The EC50 was > 44 mg/l the highest level that could be tested
due to evaporation of the test space into the head space above the
medium. The EcoSar model v0.99 predicted the EC50 for
1,1,1-trifluoroethane to be 71 mg/l. As a final evaluation, data from
1,1,1,2 -tetrafluoroethane we used as read across for the effects on
Pseudomonous putida. The 6 -hr EC50 was found to be > 730 mg/l, the
highest level tested. In summary, data from trifluoroethane,
chlorodifluoroethane and tetrafluoroethane indicate that trifluoroethane
is not toxic.
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