Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 206-996-5 | CAS number: 420-46-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Stability
A photochemical trajectory model has calculated a photochemical ozone creation potential (POCP) of zero for the test substance (HFC-143a) demonstrating a negligible contribution to photochemical ozone production (Hayman and Derwent, 1997).
Several national and international reports and studies are available that provide global warming potential (GWP) values for the test substance (generally reported as HFC-143a). Transport modelling has predicted an atmospheric lifetime of 1,1,1,-trifluoroethane to be 47.2 years (Naik et al, 2000) compared with 53.5 years as previously reported by Grainer et al (1999). In addition, the IPCC’s Fourth Assessment Report predicted an atmospheric lifetime of 52 years.
The substance is non-ozone depleting but is a global warming substance. The substance is a gas and expected to fully partition to the air compartment with an estimated half-life in air of up to 53.5 years, using the most conservative estimate. Releases of HFCs are unlikely to cause damage at a local level, but they do have a global environmental effect as greenhouse gases contribute to global warming. Although their global warming potential is high (up to 3800 times for HFC-143a over a 100 year horizon), the relatively small amounts involved mean that they play a small role compared to other greenhouse gases.
Biodegradation
Based on calculations using EpiWin software (US EPA, 2008) 1,1,1,-trifluoroethane is predicted to have a very short residence time in aqueous bodies. It is also predicted that it will not biodegrade, but will volatize into the atmosphere.
Bioaccumulation
The substance is not likely to bioaccumulate through the ecosystem. The substance has a predicted Log Kow of <1.35 (at 20 degrees C) and high vapour pressure at ambient conditions indicating a low potential for bioaccumulation.
Transport and Distribution
A Henry's Law constant of 11.2 kPa m3/mol has been reported in the Physical Properties Handbook.
The substance is only released to the atmosphere during manufacture and use. Fugacity-based modelling (US EPA, 2008) predicts that upon release to the air over 99.9% will remain in the air and less than 0.1% will partition into the combined soil and water compartments. Therefore, due to its high Henry's Law constant of 11.2 kPa m3/mol and low adsorption potential, it will partition mainly to the atmosphere following emission to the environment.
Additional information
No additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.