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Short-term toxicity to fish

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Description of key information

An acute fish toxicity study was conducted to determine the dose levels for an 8 week bioconcentration study.  The investigation was a semi-static test
consisting of a control and a range of 5 increasing concentrations of MODA to Japanese rice fish. Mortalities were observed over a 48 hour period.
The results obtained determined the 48 hour LC50, which was found to be 73.6 mg/Litre under the test conditions.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
73.6 mg/L

Additional information

An acute fish toxicity study was conducted to determine the dose levels for an 8 week bioconcentration study. The acute study was conducted according to 'Acute Toxicity Studies in Fish (71, JIS K 0102-1993)' and to the principles of GLP. The investigation was a semi-static test consisting of a control and a range of 5 increasing concentrations of MODA to Japanese rice fish.

This study is equivalent to EC 440/2008 fish toxicity guidelines except from mortalities were observed over a 48 hour period instead of 96 h. However, it can be assumed that a prolonged test duration would not have a relevant influence on the test results and the range of LC50. The results obtained determined the 48 hour LC50, which was found to be 73.6 mg/Litre under the test conditions.