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EC number: 700-111-0
CAS number: 148528-05-6
Freshwater aquatic toxicity data are available for three trophic
levels: fish, invertebrates and algae. An
acute fish toxicity study was conducted to determine the dose levels for
an 8 week bioconcentration study. Mortalities
were observed over a 48 hour period. The results obtained determined the
48 hour LC50, which was found to be 73.6 mg/L under
the test conditions. The
48-hour EC50 of MODA for the immobilisation of Daphnia magna in
non-adjusted media was 37.5 mg/L (95% confidence limits of 34.0 and 48.6
mg/L) and in pH-adjusted media it was 62.8 mg/L (95% confidence limits
of 49.1 and 84.1 mg/L). The NOEC of MODA with Daphnia magna was 21.1 and
21.0 mg/L respectively, in non-adjusted and pH-adjusted media. Long term
exposure was not tested based on strictly controlled conditions and no
significant exposure as laid down in Annex XI section 3.2 (a). A
detailed justification is attached to this dossier.
72 hours of exposure to MODA in an alga growth inhibition test, in
non-adjusted media the EbC50 and ErC50, were 22.0 and 34.4 mg/L
respectively. In pH-adjusted media, the EbC50 and ErC50, were 69.3 and
>100 mg/L respectively. The NOEC for the area under the growth curve and
for growth rate in non-adjusted media were 0.82 and 1.84 mg/L
respectively and in pH-adjusted media both were 22.0 mg/L.
toxicity test to microorganisms is not required if there is no emission
of the substance to a sewage treatment plant. Testing is waived on the
basis that there is no emission of MODA to a sewage treatment plant.
results obtained from the acute toxicity tests with daphnia and algae
suggest that the pH of the test media, increased by the presence of the
test substance, was partially responsible for the toxicity observed in
the non-adjusted media.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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