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The data submitter has no data, even after literature search on the substance (3R)-3-Amino-1-butanol, CAS 61477-40-5 to properly derive classification and labeling. Nevertheless, in order to address aquatic toxicity endpoints of the test item, reference to the racemic mixture of 3 -Amino-butan-1 -ol (CAS 2867 -59 -6) was made for read-across purposes. The Limit-test on short term toxicity to aquatic invertebrates reveals EC50>100 mg/L (BASF SE 50E0406/13X125) for 3 -Amino-butan-1 -ol (CAS 2867 -59 -6). The screening test on Toxicity to aquatic algae and cyanobacteria reveals an EC50>10 - < 100mg/L (BASF SE 86E0406/13G195) for 3 -Amino-butan-1 -ol (CAS 2867 -59 -6). Study on toxicity to microorganisms reveal EC20= 780mg/L for 3 -Amino-butan-1 -ol (CAS 2867 -59 -6). Due to these results the substance (3R)-3 -Amino-1 -butanol (CAS 61477 -40 -5) was classified as acutely harmful for the environment.