Registration Dossier
Registration Dossier
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EC number: 221-657-1 | CAS number: 3179-47-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
There is no information concerning toxicity to aquatic algae and cyanobacteria for n-Decyl methacrylate available. The results of the aquatic
toxicity to aquatic algae and cyanobacteria studies on the structurally closely related Isodecyl methacrylate (i-C10-Ester) are considered as
representative for the aquatic algae and cyanobacteria toxicity of n-Decyl methacrylate (C10 -Ester).
In a valid OECD 201 GLP study on Isodecyl methacrylate, The 72h-NOEC-values for inhibition of specific growth rate of freshwater algae (Desmodesmus subspicatus) was 12.0μg/L. The according 72h-EC50-value was > 16.9 μg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 16.9 µg/L
- EC10 or NOEC for freshwater algae:
- 12 µg/L
Additional information
There is no information concerning toxicity to aquatic algae and cyanobacteria for n-Decyl methacrylate available. The results of the aquatic toxicity to aquatic algae and cyanobacteria studies on the structurally closely related Isodecyl methacrylate (i-C10-Ester) are considered as representative for the aquatic algae and cyanobacteria toxicity of n-Decyl methacrylate (C10 -Ester).
In a fully valid GLP study according to OECD 201, Isodecyl methacrylate was found to inhibit the growth of the freshwater green alga Desmodesmus subspicatus after 72 h.
The NOEC-values for inhibition of specific growth rate and inhibition of yield after 72 h were 12.0 and 9.20 μg/L, respectively. The LOEC-values for inhibition of specific growth rate and inhibition of yield after 72 h were 16.9 and 12.0 μg/L, respectively. The EC50-values for inhibition of specific growth rate (ErC50) and yield (EyC50) after 72 h were > 16.9 and 14.1 (12.6 – 16.1) μg/L, respectively. All effect levels are given based on geometric mean measured concentrations.
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