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EC number: 201-188-9
CAS number: 79-24-3
Table 1 Summary of Primary Eye Irritation Scores
According to the classification used, the two most severe readings would equate to moderately and mildly irritating. In the case of the rabbit with a score of 18, the cornea opacity and area was rated a 1 and 1, respectively. Iris was rated a 1. Conjunctival rednes, chemosis, and discharge were 2, 1 and 1, respectively. By 48 hours, the only positive symptoms in this rabbit was conjunctival redness and chemosis which were 2 and 1, respectively. Thus the observed effects were considered to be minimal even though the rating scheme would classify the effect as moderate.
The eye irritation potential was evaluated using the U.S. Federal Hazardous Substances Act Regulation (16 CFR Part 1500). Based on the results of this test, nitroethane is equivocal as a primary eye irritant. The maximum average eye irritation score was 6.2 at 24 hours after dose administration. Based on this score, nitroethane is considered mildly irritating to rabbit eyes.
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