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Auto flammability

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auto-ignition temperature (liquids)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19-03-2019 until 30-04-2019
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
EU Method A.15 (Auto-Ignition Temperature (Liquids and Gases))
Version / remarks:
(EC) 440/2008, Annex Part A
GLP compliance:
yes (incl. QA statement)
Auto-ignition temperature:
ca. 515 °C
Atm. press.:
ca. 98.7 kPa
Remarks on result:
other: Time lag to autoignition: 26s
The autoignition temperature of 2,2'-MDI (EC Number: 219-799-4) has been determined to be 515°C.
Executive summary:

Test Objective and Information

The test covers the determination of hot and cool flame autoignition temperatures of a liquid chemical in air at atmospheric pressure in a uniformly heated vessel.

A small, metered sample of the product to be tested is inserted into a uniformly heated 500 ml glass flask containing air at a predetermined temperature. The contents of the flask are observed in a dark environment for 10 minutes following insertion of the sample, or until autoignition occurs. Autoignition is identified by the sudden appearance of a flame inside the flask and by a sharp rise in the temperature of the gas mixture. The lowest internal flask temperature at which the hot-flame ignition occurred for a series of prescribed sample volumes is taken to be the hot-flame autoignition (AIT) of the chemical in air at atmospheric pressure. Ignition delay times (ignition time lags) are measured in order to determine the ignition delay / ignition temperature relationship. The lowest temperature at which cool flames (CFT) are observed is also recorded. In all instances the ignition delay times are recorded.

The test is conducted in accordance with the procedure described in EU Regulation (EC) 440/2008, Annex Part A test A.15.

The autoignition temperature of 2,2'-MDI (EC Number: 219-799-4) has been determined to be 515°C.

Hot flame autoignition temperature (AIT,C): 515
Including correction factor for barometric pressure (°C): 515

Time lag to autoignition (s): 26
Barometric pressure (kPa): 98.7
Test Item quantity (μl): 200
Relative Humidity (%): 47


No cool flames were observed. Ignition produced an orange flame.

Description of key information

The autoignition was observed up to 515°C following EU method A.15.

Key value for chemical safety assessment

Autoflammability / Self-ignition temperature at 101 325 Pa:
515 °C

Additional information