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Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

SI's were all less than 1 hence the susbtance FP-100 is not sensitising


Migrated from Short description of key information:
In the study the test item FP-100 dissolved in acetone:olive oil 4+1 (v:v) was assessed for its possible contact allergenic potential.

For this purpose a local lymph node assay was performed using test item concentrations of 6.25, 12.5, 25%.

The animals did not show any clinical signs during the course of the study and no cases of mortality were observed.

In this study Stimulation Indices (SI.) of 0.83, 0.62, and 0.54 were determined with the test item at concentrations of 6.25, 12.5, 25% in acetone:olive oil 4+1 (v:v), respectively. The EC3 value could not be calculated, since all SI’s are below 3.

The test item FP-100 was not a skin sensitiser in this assay.

Justification for classification or non-classification