Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is classified as corrosive to the skin
Cross-reference
Reason / purpose for cross-reference:
reference to other study
Reference
Endpoint:
skin corrosion: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 435 (In Vitro Membrane Barrier Test Method for Skin Corrosion)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Hessisches Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz
Test system:
artificial membrane barrier model
Source species:
other: proprietary biobarrier membrane
Cell type:
other: proprietary biobarrier membrane
Cell source:
other: proprietary biobarrier membrane
Source strain:
other: proprietary biobarrier membrane
Vehicle:
other: no vehicle use, solution
Control samples:
yes, concurrent negative control
yes, concurrent positive control
Irritation / corrosion parameter:
other: time interval of colour change
Value:
13
Vehicle controls validity:
not examined
Negative controls validity:
valid
Positive controls validity:
valid
Remarks on result:
other: corrosive, GHS 1B
Interpretation of results:
Category 1B (corrosive) based on GHS criteria
Conclusions:
Copper(II) fluoborate solution 50 % is corrosive to skin GHS cat 1b

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion