Copper(2+) tetrafluoroborate(1-)

Acute Toxicity: dermal

Administrative data

Endpoint:

acute toxicity: dermal

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is classified as corrosive to the skin

Cross-reference

Reason / purpose for cross-reference:

reference to other study

Reference

Endpoint:

skin corrosion: in vitro / ex vivo

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 435 (In Vitro Membrane Barrier Test Method for Skin Corrosion)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Hessisches Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz

Test system:

artificial membrane barrier model

Source species:

other: proprietary biobarrier membrane

Cell type:

other: proprietary biobarrier membrane

Cell source:

other: proprietary biobarrier membrane

Source strain:

other: proprietary biobarrier membrane

Vehicle:

other: no vehicle use, solution

Control samples:

yes, concurrent negative control

yes, concurrent positive control

Irritation / corrosion parameter:

other: time interval of colour change

Value:

13

Vehicle controls validity:

not examined

Negative controls validity:

valid

Positive controls validity:

valid

Remarks on result:

other: corrosive, GHS 1B

Interpretation of results:

Category 1B (corrosive) based on GHS criteria

Conclusions:

Copper(II) fluoborate solution 50 % is corrosive to skin GHS cat 1b