Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Freie und Hansestadt Hamburg
Test type:
acute toxic class method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Copper(2+) tetrafluoroborate(1-)
EC Number:
253-959-4
EC Name:
Copper(2+) tetrafluoroborate(1-)
Cas Number:
38465-60-0
Molecular formula:
BF4.1/2Cu
IUPAC Name:
copper(2+) bis(tetrafluoroboranuide)
Constituent 2
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
water
Test material form:
other: 50% solution in water

Test animals

Species:
rat
Strain:
Crj: CD(SD)
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: hydroxypropylmethylclellulose
Control animals:
no

Results and discussion

Effect levelsopen allclose all
Key result
Sex:
male/female
Dose descriptor:
LD0
Effect level:
ca. 300 mg/kg bw
Based on:
other: 50% solution
Remarks on result:
not determinable due to absence of adverse toxic effects
Key result
Sex:
female
Dose descriptor:
LD100
Effect level:
ca. 2 000 mg/kg bw
Based on:
other: 50% solution
Mortality:
dose: 300 mg/kg bw: 0% withhin 14d
dose: 2000 mg/kg bw: 100% within 6h

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
LD50 (Copper(II) fluoborate, soliution 50%) 300< LD50 <2000 mg/kg bw