Registration Dossier
Registration Dossier
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EC number: 253-959-4 | CAS number: 38465-60-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 435 (In Vitro Membrane Barrier Test Method for Skin Corrosion)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Hessisches Ministerium für Umwelt, Energie, Landwirtschaft und Verbraucherschutz
Test material
- Reference substance name:
- Copper(2+) tetrafluoroborate(1-)
- EC Number:
- 253-959-4
- EC Name:
- Copper(2+) tetrafluoroborate(1-)
- Cas Number:
- 38465-60-0
- Molecular formula:
- BF4.1/2Cu
- IUPAC Name:
- copper(2+) bis(tetrafluoroboranuide)
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- water
- Test material form:
- other: 50% solution in water
Constituent 1
Constituent 2
In vitro test system
- Test system:
- artificial membrane barrier model
- Source species:
- other: proprietary biobarrier membrane
- Cell type:
- other: proprietary biobarrier membrane
- Cell source:
- other: proprietary biobarrier membrane
- Source strain:
- other: proprietary biobarrier membrane
- Vehicle:
- other: no vehicle use, solution
- Control samples:
- yes, concurrent negative control
- yes, concurrent positive control
Results and discussion
In vitro
Results
- Irritation / corrosion parameter:
- other: time interval of colour change
- Value:
- 13
- Vehicle controls validity:
- not examined
- Negative controls validity:
- valid
- Positive controls validity:
- valid
- Remarks on result:
- other: corrosive, GHS 1B
Applicant's summary and conclusion
- Interpretation of results:
- Category 1B (corrosive) based on GHS criteria
- Conclusions:
- Copper(II) fluoborate solution 50 % is corrosive to skin GHS cat 1b
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