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EC number: 219-616-8
CAS number: 2481-94-9
Other details not known
Skin sensitization study was performed
in human patients suffering from pigmented contact dermatitis caused by
the commercial Brilliant Lake Red R to evaluate the skin sensitizing
potential of the test substance
1-[(2,4-dimethylphenyl)diazenyl]-2-naphthol (CAS No: 3118-97-6).
The patch of
1-[(2,4-dimethylphenyl)diazenyl]-2-naphthol was applied onto the back of
each patient for 24 hours by usingFinn Chambers® on Scanpor® (Epitest,
Ltd. Oy). After removal of patch, skin reactions were assessedaccording
to the ICDRG classification for 2 days.
Twenty-eight healthy female
volunteers, aged 20 and 21, were also tested with the sample as
controls. None gave a positive reaction to
Since thepositive reactions were seen
in 2 out of total 8 cases,the test
chemical1-[(2,4-dimethylphenyl)diazenyl]-2-naphthol (CAS No:
3118-97-6)was considered to be sensitizingin human patients suffering
from pigmented contact dermatitis caused by the commercial Brilliant
Lake Red R.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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