Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-616-8
CAS number: 2481-94-9
of N,N-diethyl-p-(phenylazo)aniline for effects in the environment:
chemical N,N-diethyl-p-(phenylazo)aniline (CAS no. 2481-94-9) is used in
as a dye for plastics and inks. The aim was to assess whether the PBT
criterion within Annex XIII was fulfilled for
N,N-diethyl-p-(phenylazo)aniline. The PBT criterion was herein assessed
based on experimental data in conjunction with standardized
environmental fate models. Here follows a description of the PBT
tested substance fulfils the P criterion within Annex XIII based on the
assessment that here follows:
a prediction done by SSS (2017) using OECD QSAR toolbox version 3.3 with
log Kow as the primary descriptor, percentage biodegradability of test
chemical4-(Diethylamino)azobenzene (CAS No. 2481-94-9) was estimated.
Test substance undergoes 14% degradation by BOD in 28 days. Thus, based
on percentage degradation, the test chemical 4-(Diethylamino)azobenzene
was estimated to be not readily biodegradable in water.
another prediction using the Estimation Programs Interface Suite (EPI
suite, 2017), the biodegradation potential of the test
compound4-(Diethylamino)azobenzene(CAS No. 2481-94-9) in the presence of
mixed populations of environmental microorganisms was estimated. The
biodegradability of the substance was calculated using seven different
models such as Linear Model, Non-Linear Model, Ultimate Biodegradation
Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI
Non-Linear Model and Anaerobic Model (called as Biowin 1-7,
respectively) of the BIOWIN v4.10 software. The results indicate that
chemical 4-(Diethylamino)azobenzene is expected to be not readily
results from the similar substances (CAS: 119-93-7; 834-12-8 and
2095-06-9) also indicate that they are not readily biodegradable
to the fugacity model levels III, the most likely environmental fate for
this test chemical is soil (i.e.estimated to 80.4%). In soil,
N,N-diethyl-p-(phenylazo)aniline was expected to have negligible to slow
mobility based upon a LogKOC
in the range 1.9-4.4. Thehalf-life
in soil (120 days estimated by EPI suite) indicates that the chemical is
not persistent in soil and the exposure risk to soil dwelling animals is
moderate to low.
released in to the environment, 12.6% and 6.93% of the chemical will
partition into water and sediment according to the Mackay fugacity model
level III in EPI suite version 4.1 (2017). However, the half-life (60
days in water and 541.6 days in sediment as estimated by EPI suite)
indicates that the substance is persistent in both the compartments.
the half-life values indicate the chemical to be Very persistent (vP),
since only predicted data is available for the substance, it has been
concluded that N,N-diethyl-p-(phenylazo)aniline is not persistent in
tested substance fulfils the B criterion within Annex XIII based on the
assessment that here follows:
BCF value from authoritative database was determined to be 31.2 - 9730
water partition coefficient of the test chemical is 5.27 which is more
than the threshold of 4.5. If this chemical is released into the aquatic
environment, there should be a moderate to high risk for the chemical to
bioaccumulate in fish and food chains.
the BCF value indicate the chemical to be Very bioaccumulative (vB),
since only predicted data is available for the substance and the octanol
water partition coefficient is also just above the threshold, it has
been concluded that N,N-diethyl-p-(phenylazo)aniline is bioaccumulative
and food chains.
tested substance does not fulfil the T criterion within Annex XIII based
on the assessment that here follows:
tested chemical is regarded to be not classified for carcinogenicity,
mutagenicity and reprotoxicity, Further, there
is no evidence of chronic toxicity, as identified by the classifications
STOT (repeated exposure), category 1(oral, dermal, inhalation of
gases/vapours, inhalation of dust/mist/fume) or category 2 (oral,
dermal, inhalation of gases/vapours, inhalation of dust/mist/fume).
of the available short-term eco-toxicity estimations for invertebrates
and algae for the substance indicates the LC50/EC50 value to be in the
range 11.1 – 12.8 mg/L. These value suggest that the substance is likely
to be hazardous to Aquatic organisms at environmentally relevant
concentrations and can be considered as classified in Aquatic chronic
category 3 as per the CLP regulation.
are no available long-term toxicity evaluations for
N,N-diethyl-p-(phenylazo)aniline. By speculation, long-term NOEC for
aquatic organisms were not expected for the substance at concentration
below 0.01 mg/L based on the data mentioned above
chemical was therefore not considered as hazardous to aquatic
environments as per the criteria set out in Annex XIII.
on critical, independent and collective evaluation of information
summarized herein, the tested compound fulfil the P and B criterion but
does not fulfil the T criterion and has therefore not been classified as
a PBT compound within Annex XIII.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Tato webová stránka používá cookies, aby se vám naše stránky používaly co nejlépe.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again