Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to soil microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to soil microorganisms
Type of information:
experimental study planned
Study period:
After approval by ECHA
Qualifier:
according to guideline
Guideline:
OECD Guideline 216 (Soil Microorganisms: Nitrogen Transformation Test)
Principles of method if other than guideline:
The study is to be conducted with the hydrolysis product of the registered substance, in view of its hydrolysis rate - see IUCLID Section 6.3, CSR Section 7.2, for further details of the risk assessment approach.

Description of key information

Key value for chemical safety assessment

Additional information

No soil microorganisms toxicity data are available with N-[3-(dimethoxymethylsilyl)propyl]ethylenediamine (CAS 3069-29-2).

An OECD TG 216 study is proposed with the registration substance.

Toxicity was observed in the aquatic microorganism test (IUCLID Section 6.1.7, CSR Section 7.4), read across from a structural analogue (16 hour EC50 67 mg/L; EC10 25 mg/L (Pseudomonas putida, growth rate) (Diefenbach, 1994)). ECHA guidance Chapter R.7c (ECHA 2017) states “Where inhibition of sewage sludge microbial activity has been observed in Annex VIII testing, a test on soil microbial activity will additionally be necessary for a valid PNEC to be derived.” A soil microorganisms nitrogen inhibition test (OECD 216) is therefore proposed.

Categories Display