Registration Dossier
Registration Dossier
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EC number: 423-970-0 | CAS number: 182926-43-8 ORANGE DER 8089
Endpoint summary
Administrative data
Description of key information
Additional information
Study reports have been available for acute tests with fish, invertebrates, algae and micro-organism. The results are summarized as below:
FAT 45176/A was tested for its acute toxicity to Zebra fish in a 96 h static test. The study was performed in compliance with the OECD Guideline for Testing of Chemicals. In all test concentrations no mortalities of the Fish was observed after the test period of 96 hours. During the test the actual test concentration in the analysed test medium was in the range of 10 - 70 % of the nominal values. Therefore, the reported results are related to the actual mean concentrations of the test substance and the LC50 value is above the water solubility of the test substance in the test medium of 33 mg/L.
FAT 45176/A was tested for its acute toxicity to Daphnia magna in a 48 h static test. No immobilization and abnormal behaviour of the Daphnia was observed in the control and in the test concentration of 259 mg/l.Thus, the EC50 value after 48 h was higher than 259 mg/l.
The influence of the test substance FAT 45'176/A on the growth of the green algal species Scenedesmus subspicatus CHODAT was investigated in a 72-h static test according to the OECD Guideline No. 201. However, the test method was modified to quantify the algicidal effect of the test substance, but also the growth inhibition effect caused by reduced light intensities in the coloured test solutions. In this experimental part FAT 45'176/A had a statistically significant inhibition effect on the growth of Scenedesmus subspicatus after the exposure period of 72 h first at the concentration of 3.2 mg test substance/l (= 72-h LOEC: lowest concentration tested with toxic effects). The 72-h NOEC (highest concentration tested without toxic effects) was 1.0 mg test substance/l, since at this test concentration the mean growth rates of the algae were statistically not significantly lower than in the control. The 72 h EC50 based on growth rate was above 100 mg/l.
The toxicity of FAT 45176/A to activated sludge was determined in a 3-h respiration inhibition test according to the OECD Guideline No. 209 and used as the key study. The test substance concentrations tested were 320, 100, 32 and 10 mg/l. The IC50(3 h) of the test substance FAT 45176/A was >320 mg/l.
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