Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Study reports have been available for the ready biodegradability test, inherent biodegradability test, hydrolysis as a function of pH, bioaccumulation test and adsorption / desorption test. The results are summarized as below:

 

From the results of the ready biodegradability test (degradation: 0 % on day 28) and BOD5/COD ratio (BOD5/COD=1.6 %), it can be concluded the test substance is not readily biodegradable. The inherent biodegradability test was available according to OECD Guideline 302B. The biodegradation of test substance on day 28 was 18 %. Therefore, FAT 45'176/A was found to be slightly biodegradable over the 28-day exposure period under the test conditions.

 

Hydrolysis as a function of pH was performed under GLP compliance and used as the key study. The result showed FAT 45176/A at pH 4 has a half-life period of 12233.9 hours (about 1.4 years) at 25 °C, at pH 7 has a half-life period of 84.8 hours (about 3.5 days) at 25 °C, and is unstable at pH 9 with a half-life period of shorter than one day at 25 °C.

 

Bioaccumulation test of FAT45'176/A in carp was performed under GLP compliance and used as the key study. The bioconcentration factors were<=0.6 in level 1 and <=5.6 in level 2 for peak 1, and <=4.1 in level 1 and <=40 in level 2 for peaks 1, 2 and 3.

 

The adsorption and desorption of FAT 45'176/A were determined in a screening test by the batch equilibrium method using three soils: Speyer (loamy sand), Les Barges (silt loam) and Sisseln (sandy loam) under GLP compliance and used as the key study. The result showed the KOC values were 1105 ml/g, 1156 ml/g and 1249 ml/g for soils, Sisseln and Les Barges, respectively. FAT 45'176/A can therefore be regarded as little mobile in soils.