Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-07-13 - 2011-08-26
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Name of test material (as cited in study report): Capa™ 2043
- Substance type: organic
- Physical state: Liquid
- Analytical purity: Mixture(GC purity) 1,4-butandiol 1.7 % , 1,4-butandiol -1ECL 11.1 %, 1,4-butandiol -2ECL 21.6 %, 1,4-butandiol -3ECL 24.8 %, 1,4-butandiol -4ECL 20.6 %, 1,4-butandiol -5ECL 12.9 %, 1,4-butandiol -6ECL 5.9 %, 1,4-butandiol -7ECL 1.6 %
- Lot/batch No: WNI 342 27/1/09 WAC000378
- Stability under test conditions: good
- Storage condition of test material: room temperature

Results and discussion

Water solubilityopen allclose all
Water solubility:
6.7 g/L
Temp.:
20 °C
Remarks on result:
other: Sum of CAPA*; CAPA (0.5g/50ml)
Water solubility:
29 g/L
Temp.:
20 °C
Remarks on result:
other: Sum of CAPA*; CAPA (5g/50ml)
Water solubility:
0.1 g/L
Temp.:
20 °C
Remarks on result:
other: 1,4-butandiol, CAPA (0.5g/50ml)
Water solubility:
0.8 g/L
Temp.:
20
Remarks on result:
other: 1,4- butandiol, CAPA (5g/50ml)

Any other information on results incl. tables

Flask

Water Solubility, g/l

(CAPA 0.5g/50ml)

Water Solubility, g/l

(CAPA 5g/50ml)

1 (3 days)

6.87 (Sum of CAPA*)
0.14 (
1,4-butandiol)

28.6 (Sum of CAPA*)
0.75 (
1,4-butandiol)

1 (6 days)

6.70 (Sum of CAPA*)
0.14 (
1,4-butandiol)

29.5 (Sum of CAPA*)
0.75 (
1,4-butandiol)

1 (9 days)

6.64 (Sum of CAPA*)
0.14 (
1,4-butandiol)

29.2 (Sum of CAPA*)
0.83 (
1,4-butandiol)

*Sum of CAPAis the average value of the three oligomers; from 1,4-butandiol-1ECL to 1,4-butandiol-3ECL.

Flask

pH in water phase(0.5g/50ml)

pH in water phase(5g/50ml)

1 (3 days)

4.4

4.0

1 (6 days)

4.9

3.9

1 (8 days)

4.5

3.9

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L) and very soluble (> 10000 mg/L)
Water solubility at 20°C is 6.7 g/l (0.5g/50ml) and 29 g/l (5g/50ml)
Executive summary:

 

CAPA (0.5g/50ml)

CAPA (5g/50ml)

Component

Concentration (g/l)

Concentration (g/l)

Sum of CAPA*

6.7

29

Sum of CAPA is the average value of the three oligomers; from 1,4-butandiol-1ECL to 1,4-butandiol-3ECL.