Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There is a single, key study for sensitization of the aromatic sulphonic acids. None of the tested animals showed positive responses in a, well documented, GLP guinea pig sensitization study (Hoechst, 1988) with toluene-4-sulphonic acid (CAS No. 104-15-4). The test substance can be considered a non-sensitizer in guinea pigs as none of the test animals showed a positive response to combined intradermal and topical induction followed by topical challenge

Migrated from Short description of key information:
Not sensitizing

Justification for classification or non-classification

There is no human or animal evidence on this endpoint therefore no classification is warranted under 67/548/EEC or Regulation 1272/2008.