Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Oxidising properties
Administrative data
- Endpoint:
- oxidising solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-01-12 to 2021-03-01
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4-chloro-N-[2-methoxy-4-(morpholin-4-yl)-5-nitrophenyl]pyrimidin-2-amine
- Cas Number:
- 2270944-70-0
- Molecular formula:
- C15H16ClN5O4
- IUPAC Name:
- 4-chloro-N-[2-methoxy-4-(morpholin-4-yl)-5-nitrophenyl]pyrimidin-2-amine
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Test results (Oxidising solids)open allclose all
- Sample tested:
- reference: 3:7 mixture potassium bromate + cellulose
- Parameter:
- mean burning time
- Result:
- 118 s
- Sample tested:
- 4:1 sample-to-cellulose ratio
- Parameter:
- mean burning time
- Result:
- 144 s
- Sample tested:
- 1:1 sample-to-cellulose ratio
- Parameter:
- mean burning time
- Result:
- > 180 s
Any other information on results incl. tables
The mean burning time of both test item mixtures was more than the mean burning time of the 3:7 (w/w) reference mixture. According to this, the test item has no oxidizing properties.
The burning time of 4:1 of the test item mixture is the time of reaction. The mixture reacted during the test (i.e. expansion, lots of smoke). No burning with flames was observed.
| Potassium bromate/cellulose (w/w) | Burning time (s) | Mean burning time (s) |
| 3:7 | 120 110 | 118 |
Table 5: Burning rates of Test Item/ Cellulose Mixtures
| Test item/cellulose (w/w) | Burning time (s) | Mean burning time (s) |
| 4:1 | 1461 1501 1451 1391 1411 | 1441 |
| 1:1 | >180 >180 >180 >180 >180 | >180 |
1 Time when reaction stopped
Applicant's summary and conclusion
- Conclusions:
- The full test was performed to monitor the oxidizing properties of JNJ-73848242-AAA
(T003901).
Based on the results obtained it was concluded that the test item has no oxidizing properties
and is therefore not classified as a Division 5.1 substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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