Registration Dossier
Registration Dossier
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EC number: 448-020-2 | CAS number: -
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.059 mg/m³
- Most sensitive endpoint:
- repeated dose toxicity
DNEL related information
- Overall assessment factor (AF):
- 150
- Modified dose descriptor starting point:
- LOAEC
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.017 mg/kg bw/day
- Most sensitive endpoint:
- repeated dose toxicity
DNEL related information
- Overall assessment factor (AF):
- 600
- Modified dose descriptor starting point:
- LOAEL
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
Dusantox L is used as a stabilizer and antioxidant in polymerization process in production of resins, rubbers and polymer. Concerning occupational exposure, workers may be exposed to Dusantox L during sampling. Exposure of consumers or men via the environment to Dusantox L is not expected. Based on all information available, DNELs were derived for workers only. Occupational exposure is most likely to occur through inhalation and dermal contacts. Hence, DNELs were derived for dermal and inhalatory routes of exposure.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
Dusantox L is used as a stabilizer and antioxidant in polymerization process in production of resins, rubbers and polymer. Concerning occupational exposure, workers may be exposed to Dusantox L during sampling. Exposure of consumers or men via the environment to Dusantox L is not expected. Based on all information available, DNELs were derived for workers only. Occupational exposure is most likely to occur through inhalation and dermal contacts. Hence, DNELs were derived for dermal and inhalatory routes of exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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