Registration Dossier
Registration Dossier
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EC number: 852-824-2 | CAS number: 1404220-73-0
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Assessment of PBT/vPvB Properties
Persistence (P, vP)
Doverphos 374 hydrolyses rapidly, as such, abiotic degradation is expected to be the dominant pathway for it in the environment.
Based on the very short half-lives in water, Doverphos 374 is not expected to meet the criteria for P or vP. The hydrolysis products of Doverphos 374 are biodegradable and also do not meet the criteria for P or vP.
Several recent biodegradation studies of alkyl and aryl phosphites, including triisotridecyl phosphite and triphenyl phosphite, show that this class of phosphites are readily biodegradable when the test system is properly designed for the properties of the substance.
Bioaccumulation (B, vB)
Bioaccumulation concentration factor (BCF) cannot not be measured for Doverphos 374 due to its rapid hydrolysis. The BCF model estimates for the primary constituent in Doverphos 374 are generally low. Given the rapid hydrolysis, the bioaccumulation potential of the hydrolysis products was also considered and these are likewise below the criterion for B (bioaccumulative) or vB (very bioaccumulative). As such, it is concluded that Doverphos 374 does not meet the criteria for B or vB.
Toxicity (T)
Doverphos 374 has a low order of toxicity to mammalian species. The primary effect is skin sensitisation; for which it is classified.
Based on Doverphos 374 ’s very low water solubility it is not anticipated to cause aquatic toxicity directly. Further, its water solubility level is orders of magnitude below the aquatic toxicity levels of its hydrolysis products. One of its hydrolysis products (para-cumyl phenol - PCP) is classified as dangerous to the environment (Aquatic Acute 1 and Aquatic Chronic 2). Based on the relative amounts of PCP groups in Doverphos 374 a classification of Aquatic Chronic 3 (H412) has been added as a conservative measure.
PBT/vPvB criteria and justification
Doverphos 374 is not classifiable as a PBT or a vPvB substance as it does not meet criteria for either persistence or bioaccumulation and toxicity effects are primarily related to its potential for sensitisation.
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