Carboxylic acids, C5-9

Toxicity to terrestrial arthropods

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

toxicity to terrestrial arthropods: short-term

Type of information:

experimental study

Adequacy of study:

other information

Study period:

Study performed in 1993.

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

Data from reliable database, but information not required by REACH (The scope of the terrestrial effect assessment under the adopted REACH regulation is restricted to soil organisms in a narrow sense, i.e. on non-vertebrate organisms living the majority of their lifetime within the soil and being exposed to substances via the soil pathway and in line with the previous practice in the environmental risk assessment of new and existing substances in the EU.)

Qualifier:

according to guideline

Guideline:

EPA OPP 141-1 (Honey Bee Acute Contact Toxicity)

GLP compliance:

not specified

Application method:

contact

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

Apis mellifera

Animal group:

Hymenoptera (honeybees)

Details on test organisms:

TEST ORGANISM
- Common name: Honey bee
- Age at test initiation (mean and range, SD): worker

Study type:

laboratory study

Total exposure duration:

48 h

Duration:

48 h

Dose descriptor:

LD50

Effect conc.:

> 25 µg per animal

Nominal / measured:

not specified

Conc. based on:

not specified

Basis for effect:

mortality

Reference 2

Endpoint:

toxicity to terrestrial arthropods: short-term

Data waiving:

other justification

Justification for data waiving:

other:

Description of key information

No reliable and relevant data available.

Additional information

According to the REACH requirements,

"In the absence of toxicity data for soil organisms, the equilibrium partitioning method may be applied to assess the hazard to soil organisms. The choice of the appropriate tests depends on the outcome of the chemical safety assessment. In particular for substances that have a high potential to adsorb to soil or that are very persistent, the registrant shall consider long-term toxicity testing instead of short-term. These studies do not need to be conducted if direct and indirect exposure of the soil compartment is unlikely. " (Annex IX & X)

Carboxylic acids, C5 -9 have no potential for adsorption to soils, no significant potential for bioaccumulation and is readily biodegradable. The results of aquatic studies clearly demonstrate that the target substance is not acutely toxic. A QSAR result also indicates that no toxic effect on soil macroorganisms is to be expected. Therefore, the equilibrium partitioning method is used to assess the hazard potential to soil organisms.

The results of the chemical safety assessment indicates no need to investigate further the effects of the substance and/or relevant degradation products on sediment organisms