2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)

Melting point / freezing point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

July 2015

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

HEXAMIDINE BATCH 40686

Key result

Melting / freezing pt.:

ca. 217 °C

Decomposition:

yes

Decomp. temp.:

> 292 °C

mass loss = 0.2mg

Conclusions:

Melting point by differential scanning calorimetry ca 217°C

Reference 2

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

April 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

capillary method

Specific details on test material used for the study:

Hexamidine diisethionate Batch 41519
white powder
purity 99.8%

Key result

Melting / freezing pt.:

> 213.7 - < 220.9 °C

at the end of the study the item is brown instead of white

Conclusions:

The melting point is between 213.7 and 220.9°C

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

217 °C