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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
GLP compliance:
no
Type of method:
flask method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
-1.3
Temp.:
20 °C
pH:
>= 5 - <= 7

The partition coefficient Pow of the test item was determined to be: log Pow = -1.3

Description of key information

The partition coefficient Pow of the test item was determined tobe: log Pow = -1.2

Key value for chemical safety assessment

Log Kow (Log Pow):
-1.2
at the temperature of:
20 °C

Additional information

The partition coefficient (n-octanol/water) was estimated based on the ratio of the individual solubilities of the test item in water and n-octanol. The solubilities were determined according to the flask method described in the european Commission Regulation (EC) No. 440/2008, A.6. and in the OECD Guideline 105.