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EC number: - | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From November 20, 2017 to January 17, 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- Under the study conditions, for the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation: vapour pressure at 20 °C: 3.68E-06 Pa and vapour pressure at 25 °C: 5.92E-06 Pa.
- Executive summary:
A study was conducted to determine the vapour pressure of the test substance according to OECD Guideline 104 resp. EU Method A.4 using the effusion method (weight loss), in compliance with GLP. Vapour pressure was examined at nine different temperatures. Three temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (p). Under the study conditions, for the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation: vapour pressure at 20 °C: 3.68E-06 Pa and vapour pressure at 25 °C: 5.92E-06 Pa (Muckle, 2018).
Reference
Vapour Pressures (Effusion Method):
Experiment |
T |
Mean p |
Stand. Dev. p |
RSD p |
No. |
K |
Pa |
Pa |
% |
6 |
378.2 |
2.01E-03 |
3.29E-04 |
16.4% |
7 |
393.2 |
5.48E-03 |
1.48E-03 |
27.0% |
8 |
408.2 |
1.00E-02 |
7.28E-04 |
7.3% |
The graph 1/T vs. log (P) shows a straight line with a correlation coefficient of -0.9928.
Description of key information
The vapour pressure was detrmined according to OECD Guideline 104 and EU Method A.4 (Muckle, 2018).
Key value for chemical safety assessment
- Vapour pressure:
- 20 Pa
- at the temperature of:
- 0 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
