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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From November 20, 2017 to January 17, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: vapour pressure balance
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0 Pa

Vapour Pressures (Effusion Method):

Experiment

T

Mean p

Stand. Dev. p

RSD p

No.

K

Pa

Pa

%

6

378.2

2.01E-03

3.29E-04

16.4%

7

393.2

5.48E-03

1.48E-03

27.0%

8

408.2

1.00E-02

7.28E-04

7.3%

The graph 1/T vs. log (P) shows a straight line with a correlation coefficient of -0.9928.

Conclusions:
Under the study conditions, for the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation: vapour pressure at 20 °C: 3.68E-06 Pa and vapour pressure at 25 °C: 5.92E-06 Pa.
Executive summary:

A study was conducted to determine the vapour pressure of the test substance according to OECD Guideline 104 resp. EU Method A.4 using the effusion method (weight loss), in compliance with GLP. Vapour pressure was examined at nine different temperatures. Three temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (p). Under the study conditions, for the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation: vapour pressure at 20 °C: 3.68E-06 Pa and vapour pressure at 25 °C: 5.92E-06 Pa (Muckle, 2018).

Description of key information

The vapour pressure was detrmined according to OECD Guideline 104 and EU Method A.4 (Muckle, 2018).

Key value for chemical safety assessment

Vapour pressure:
20 Pa
at the temperature of:
0 °C

Additional information