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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017 - 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Lot/batch No.of test material: 201704012 – R1704026
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
5.06
Temp.:
25 °C
pH:
6
Remarks on result:
other: weighted average log Pow
Details on results:
The log Pow of cis-Tetramethrin is 4.92 at 25 °C and pH 6; the log Pow of trans-Tetramethrin is 5.11 at 25 °C and pH 6; the weighted average log Pow is calculated and the log Pow of d-Tetramethrin is therefore 5.06 at 25 °C and pH 6.
Conclusions:
The log Pow of cis-tetramethrin is 4.92 at 25 °C and pH 6; the log Pow of trans-tetramethrin is 5.11 at 25 °C and pH 6; the weighted average log Pow is calculated and the log Pow of d-tetramethrin is therefore 5.06 at 25 °C and pH 6.
Executive summary:

The octanol/water partition coefficient of the test item d-tetramethrin (technical grade) has been determined according to the OECD test method 117: “HPLC Method”.

The log Pow of cis-tetramethrin is 4.92 at 25 °C and pH 6; the log Pow of trans-tetramethrin is 5.11 at 25 °C and pH 6; the weighted average log Pow is calculated and the log Pow of d-tetramethrin is therefore 5.06 at 25 °C and pH 6.

Description of key information

The octanol/water partition coefficient of the test item d-tetramethrin (technical grade) has been determined according to the OECD test method 117: “HPLC Method”.

The log Pow of cis-tetramethrin is 4.92 at 25 °C and pH 6; the log Pow of trans-tetramethrin is 5.11 at 25 °C and pH 6; the weighted average log Pow is calculated and the log Pow of d-tetramethrin is therefore 5.06 at 25 °C and pH 6.

Key value for chemical safety assessment

Log Kow (Log Pow):
5.06
at the temperature of:
25 °C

Additional information