Registration Dossier
Registration Dossier
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EC number: 231-561-1 | CAS number: 7632-51-1
Endpoint summary
Administrative data
Description of key information
In accordance with REACH Annex XI, section 2, testing is technically not feasible as a consequence of the properties of the substance (hydrolytically unstable substance and quasi-instantaneously degraded in contact with moist skin or mucous membranes to form Vanadium dioxide and hydrogen chloride).
And there are sufficient data on the breakdown products (vanadium dioxide n°CAS: 12036-21-4 and hydrogen chloride n°CAS: 9004-54-0) which were already registered in the frame of REACH. These breakdown substances are exempted to Registration following Annex V (Entry I) for this register dossier.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Link to relevant study records
- Endpoint:
- short-term repeated dose toxicity: oral
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Vanadium tetrachloride is quasi-instantaneously degraded in contact with moist skin or mucuous membranes to form Vanadium dioxide and hydrogen chloride.
VCl4 + H2O => VOCl2 + 4HCl
2VOCl2 + 2H2O => 2VO2 + 4HCL
Testing Vanadium tetrachloride for long term toxicity is for this reason not relevant at all, but breakdown products have to be considered (classification for Vanadium dioxide and hydrogen
chloride have been elaborated in the frame of REACH and non classification is elaborated for long term effects).
For these reasons, no classification could be set for repeated toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
