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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

No biodegradation was observed after 28days in the manometric respirometry test (OECD 301F.) . The 4-amino-m-cresol is not readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

A ready biodegradation test, following the OECD 301F guideline, was conducted on 4-amino-m-cresol. The substance was tested at 100 mg /L. The inoculum was activated sludge collected from the aeration tank of the facility's sewage treatment plant. The test treatment and inoculum blank were measured in duplicate while reference and toxicity control were measured singly. The deviation between replicate treatments was <20% (met the validity criteria of the guideline).

The % biodegradation at the end of the test was 0% indicating that 4 -amino-m-cresol was not readily biodegradable

The reference material, sodium benzoate, met the validity criteria for the test, greater than 60% biodegradation within 14 d, and within the 10 d window. The test material was not inhibitory to the test system as verified in the toxicity control.