Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 280-734-8 | CAS number: 83763-48-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 on Daphnia magna after 48 h of exposure to the test item under static conditions is 3.0 mg a.i./L (95% confidence limit = 2.34 - 3.82 mg a.i./L) expressed as mean measured concentration. The 48h-NOEC is 1.63 mg a.i./L (mean measured concentration).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3 mg/L
Additional information
The acute toxicity of the test item to Daphnia magna was tested according to the OECD guideline 202 and GLP. The study was conducted under static conditions.
20 daphnies were exposed during the 48 -hour exposure to the following mean measured concentrations 0.715 , 1.63, 3.58, 8.13, 17.8 and 36.2 mg /L, determined by High Performance Liquid Chromatography with ultraviolet detection (HPLC-UV) system. These measured concentrations represent recoveries of 82 to 89% of the nominal concentrations.
The water quality parameter (pH, oxygen) measured at the start and at the end of exposure were within the acceptable limits. No immobilisation was observed in the controls. The validity criteria of the guideline were fulfilled.
The EC50 on Daphnia magna after 48 h of exposure to the test item is 3.0 mg a.i./L (95% confidence limit = 2.34 - 3.82 mg a.i.//L) expressed as mean measured concentration. The 48h-NOEC is 1.63 mg a..i./L (mean measured concentration). This study is classified as acceptable and satisfies the guideline requirement.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
