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EC number: 701-188-3 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From June 10 to July 12, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Well described study conducted in accordance with GLP and OECD Guideline 105 with minor deviation: mean accuracy of the analytical method with frozen samples (112%) slightly above the criterion range (70-110%).
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- mean accuracy on frozen samples (112%) slightly above the criterion range (70-110%)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- mean accuracy on frozen samples (112%) slightly above the criterion range (70-110%)
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 2 540 mg/L
- Temp.:
- 20 °C
- pH:
- >= 4.7 - <= 5
- Remarks on result:
- other: prolonged stirring times of 95, 119 and 143 hours
- Details on results:
- Preliminary test: Content of test substance dissolved in water was 2.42 g/L.
Main test: See tables 1 and 2 - Conclusions:
- The water solubility of terpineol multiconstituent at 20°C obtained with stirring times of 24, 48 and 72 hours was 2847 mg/L. The pH of the aqueous samples was 5.9-6.0.
- Executive summary:
A GLP study was conducted to determine the water solubility of terpineol multiconstituent according to OECD Guideline 105, flask method.
The water solubility of terpineol at 20°C obtained with prolonged stirring times of 24, 48 and 72 hours was 2847 mg/L. The pH of the aqueous samples was 5.9 -6.0.
Reference
Table 1: Water solubility of the test substance at 24, 48 and 72 hours
Stirring time (hours) |
Analysed concentration (g/L) |
Mean (g/L) |
MD (%) |
pH |
24 |
2.52 |
2.85 |
24 |
6 |
48 |
2.81 |
5.9 |
||
72 |
3.21 |
5.9 |
Table 2: Water solubility of the test substance at prolonged stirring times of 96, 120 and 144 hours
Stirring time (hours) |
Analysed concentration (g/L) |
Mean (g/L) |
MD (%) |
pH |
95 |
2.77 |
2.54 |
14 |
4.7 |
119 |
2.45 |
4.7 |
||
143 |
2.4 |
5 |
Description of key information
The water solubility of terpineol multiconstituent at 20°C was 2847 mg/L according to OECD Guideline 105.
Key value for chemical safety assessment
- Water solubility:
- 2 847 mg/L
- at the temperature of:
- 20 °C
Additional information
This experimental value was measured in a study performed according to OECD Guideline 105 with minor deviations.
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