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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 15 to 29 June 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Well described study performed according to GLP and OECD guideline 102 without any deviation
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Type of method:
capillary method
Key result
Melting / freezing pt.:
>= -35.9 - <= -28.2 °C
Remarks on result:
other: Standard deviation (SD): 0.14 (begin) and 0.28 (end); estimated accuracy: ± 0.4 °C

Table 1: Values in pre-test

Room Temperature

5 °C

-20 °C

-80 °C

liquid

liquid

slightly frozen

solid

 

Table 2: Melting values in main study

Melting point/range

Begin

End

First determination

-36.0 °C (237.2 K)

-28.4 °C (244.8K)

Second determination

-35.8 °C (237.4 K)

-28.0 °C (245.2K)

Table 3: Validity

 

Parameter

Criterion

Found

Assessment

Difference between duplicate determinations

5.0K

0.4 K

valid

Difference between begin and end of melting process

5.0K

7.7 K

melting range is stated

Conclusions:
The melting range of terpineol multiconstituent was determined to be -35.9 to -28.2 °C (237.3 to 245 K).
Executive summary:

A GLP study was conducted to determine the melting range of terpineol multiconstituent by capillary/metal block method according to OECD Guideline 102 and EU Method A.1. The melting ranges during the first and second measurements were estimated to be -36 to -28.4 °C and -35.8 to -28.0 °C, respectively. The estimated accuracy was ± 0.4 °C.

 

The melting range of terpineol multiconstituent was determined to be -35.9 to -28.2 °C (237.3 to 245 K).

Description of key information

The melting range of terpineol multiconstituent was determined by capillary/metal block method.
The melting range of terpineol multiconstituent was determined to be -35.9 to -28.2 °C (237.3 to 245 K).

Key value for chemical safety assessment

Additional information

Key study conducted according to OECD 102 and EU A.1 guideline, under GLP without deviation and with certificate of analysis included. Therefore the result of the key study is proposed as end point value.