Registration Dossier
Registration Dossier
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EC number: 434-280-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity: The acute oral LD50 of the test material in the rat was 4570 mg/kg bw for males, and 3770 mg/kg for females
Acute dermal toxicity: The acute dermal LD50 of the test material in the rat was found to be >2000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 4 750 mg/kg bw
- Quality of whole database:
- Study has been assigned a reliability of 1.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
- Quality of whole database:
- Study has been assigned a relaaibility of 1.
Additional information
Justification for classification or non-classification
For oral oxicity, following a study condicted to EU Method B1 the following LD50 values were deteremeined,: Males LD50: 4570 mg/kg
Females: 3770 mg/kg.
Following an acute dermal toxicity study conducted to gyuideline OECD 434, an LD50 of >2000 mg/kg was determined.
In accordance with REACH (Annex VIII, Column 2) the study does not need to be conducted uf exposure of humans via inhalation is likely, taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size. It is concluded that with a low vapour pressure of 9.6E-06 Pa, determination of toxicity by inhalation did not need to be determined for this test material.
The substance is therefore not classified as toxic by acute oral, acute inhalation or acute dermal exposure.
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