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EC number: 943-330-9 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Aug 19 - Sep 5, 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Principles of method if other than guideline:
- Dissolved organic carbon method via TOC analyser
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- The TC content of the test item was determined under non-GLP conditions.
- Type of method:
- flask method
- Water solubility:
- 6.23 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Temp.:
- 20 °C
- pH:
- >= 6 - <= 7
- Remarks on result:
- other: for the following nominal concentration range of the test item in water: 10 – 100 g/L
Reference
The measurements which were included in the calculation of the mean are presented in the following table:
Measurements used for Calculation of Solubility
Flask |
Concentration [g/L] |
Total Mean [g/L] |
Total Standard Deviation [g/L] (RSD* [%]) |
2 |
5.07 |
6.23 |
0.69 (11.1 %) |
3 |
5.82 |
||
1** |
6.37 |
||
4 |
6.37 |
||
5 |
6.67 |
||
6 |
7.04 |
* RSD = relative standard deviation
** mean value of flasks 1A-C (2 – 6d), as the plateau was not reached on day 1
Mean at the plateau is 6.23 ± 0.69 g/L.
The relative standard deviation (RSD) of the determination was high (11.1 %) due to a slight dependency of the water solubility on the amount of the test item added:
Measurements used for Calculation of Solubility
Flask |
Measured Conc. Test Item [g/L] |
Nominal Conc. Test Item [g/L] |
Dissolved Part [%] |
2 |
5.07 |
10.9 |
50 |
3 |
5.82 |
30.12 |
19 |
1 |
6.37 |
50.02 |
13 |
4 |
6.37 |
60.10 |
11 |
5 |
6.67 |
80.08 |
8 |
6 |
7.04 |
100.14 |
7 |
The higher the nominal loading of the test item in water, the lower is the dissolved part of the test item.
As dissolved carbon was measured as sum parameter for dissolved test item, this study cannot distinguish between water solubility and hydrolysis of the test item.
Description of key information
6.23 g/L at 20 °C, pH >= 6 - <= 7 (OECD 105)
Key value for chemical safety assessment
- Water solubility:
- 6.23 g/L
- at the temperature of:
- 20 °C
Additional information
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